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Atherogenic dyslipidemias: unmet needs and the therapeutic potential of emerging and novel approaches and drugs
Journal article   Peer reviewed

Atherogenic dyslipidemias: unmet needs and the therapeutic potential of emerging and novel approaches and drugs

Alessandra Romandini, Damiano Baldassarre, Stefano Genovese, Stefano Capri, Giulio Pompilio, Marco Scatigna and José Pablo Werba
Pharmaceuticals, Vol.16(2), pp.1-17
2023
Scopus ID: 2-s2.0-85148937315
Web of Science ID: WOS:000940891500001
PMCID: PMC9963828
PMID: 37259324

Abstract

Drug intolerance Lipid-modifying drugs Atherogenic dyslipidemia Cardiovascular Disease
Innovative lipid-modifying agents are valuable resources to improve the control of atherogenic dyslipidemias and reduce the lipid-related residual cardiovascular risk of patients with intolerance or who are not fully responsive to a consolidated standard of care (statins plus ezetimibe). Moreover, some of the upcoming compounds potently affect lipid targets that are thus far considered “unmodifiable”. The present paper is a viewpoint aimed at presenting the incremental metabolic and cardiovascular benefits of the emerging lipid-modulating agents and real-life barriers, hindering their prescription by physicians and their assumption by patients, which need to be worked out for a more diffuse and appropriate drug utilization.
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url
https://doi.org/10.3390/ph16020176View
Published (Version of record) Open CC BY V4.0

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